# How to Research Nasdaq Biotechnology Index Companies
A useful biotechnology research process begins with company stage and asset concentration.
Clinical-stage companies
Start with:
- lead asset;
- target/biology;
- indication;
- trial design;
- endpoint;
- human efficacy;
- safety;
- next catalyst;
- cash runway;
- dilution.
Commercial-stage companies
Start with:
- product-level revenue;
- demand/volume;
- net pricing;
- payer access;
- patent/exclusivity;
- lifecycle management;
- free cash flow;
- pipeline replacement.
Platform companies
Ask whether the platform has been validated repeatedly in humans or through diversified partner economics.
Gene/cell therapy
Add:
- delivery;
- durability;
- CMC/manufacturing;
- long-term follow-up;
- treatment-center capacity.
Diagnostics/tools
Add:
- installed base;
- test/sample volumes;
- recurring consumables;
- reimbursement/research funding;
- workflow retention.
The Swoopr company pages in this package use 19 research archetypes instead of one generic biotechnology template.