# How to Research Nasdaq Biotechnology Index Companies

A useful biotechnology research process begins with company stage and asset concentration.

Clinical-stage companies

Start with:

  • lead asset;
  • target/biology;
  • indication;
  • trial design;
  • endpoint;
  • human efficacy;
  • safety;
  • next catalyst;
  • cash runway;
  • dilution.

Commercial-stage companies

Start with:

  • product-level revenue;
  • demand/volume;
  • net pricing;
  • payer access;
  • patent/exclusivity;
  • lifecycle management;
  • free cash flow;
  • pipeline replacement.

Platform companies

Ask whether the platform has been validated repeatedly in humans or through diversified partner economics.

Gene/cell therapy

Add:

  • delivery;
  • durability;
  • CMC/manufacturing;
  • long-term follow-up;
  • treatment-center capacity.

Diagnostics/tools

Add:

  • installed base;
  • test/sample volumes;
  • recurring consumables;
  • reimbursement/research funding;
  • workflow retention.

The Swoopr company pages in this package use 19 research archetypes instead of one generic biotechnology template.