---
title: "Prothena Corporation plc Metrics Guide"
description: "Prothena Corporation plc revenue, margins, cash flow and balance sheet figures by fiscal year, taken from its SEC filings, with the ratios explained."
canonical: https://www.getswoopr.com/stocks/companies/prothena-corporation-plc/financial-metrics/
source: "Swoopr Investment: https://www.getswoopr.com"
---

# Prothena Corporation plc Financial Metrics Guide

## Direct Answer

> Prothena Corporation plc reported revenue of $10 million for the fiscal year ended December 31, 2025, with an operating margin of -2216.4% and net income of -$244 million, according to its SEC filings. Revenue fell 92.8% from the prior year.

## What Are Prothena Corporation plc's Key Financial Figures?

| Fiscal year | FY2025ended December 31, 2025 | FY2024ended December 31, 2024 | FY2023ended December 31, 2023 | FY2022ended December 31, 2022 |
| --- | --- | --- | --- | --- |
| Revenue | $10 million | $135 million | $91 million | $54 million |
| Operating income | -$215 million | -$155 million | -$191 million | -$132 million |
| Operating margin | -2216.4% | -114.4% | -209.1% | -244.1% |
| Net income | -$244 million | -$122 million | -$147 million | -$117 million |
| Net margin | -2520.6% | -90.5% | -160.9% | -217.0% |
| Operating cash flow | -$164 million | -$150 million | -$134 million | -$109 million |
| Capital expenditures | Not reported | Not reported | Not reported | Not reported |
| Free cash flow | Not reported | Not reported | Not reported | Not reported |

Operating margin narrowed by 2102.1 percentage points between fiscal 2024 and 2025, which separates pricing and cost discipline from revenue growth alone.

![Bar chart of Prothena Corporation plc revenue, operating income, net income for fiscal 2022 to 2025. In fiscal 2025, revenue was $10 million, operating income negative $215 million and net income negative $244 million.](https://www.getswoopr.com/images/charts/prothena-corporation-plc-metrics-revenue-profit.webp)
*Prothena Corporation plc revenue, operating income and net income by fiscal year, from the figures in the table above. Select the chart to open it full size.*

![Line chart of Prothena Corporation plc operating margin and net margin for fiscal 2022 to 2025. In fiscal 2025, operating margin was -2216.4% and net margin was -2520.6%.](https://www.getswoopr.com/images/charts/prothena-corporation-plc-metrics-margins.webp)
*Prothena Corporation plc operating margin and net margin by fiscal year: operating income and net income as a share of revenue. Select the chart to open it full size.*

## What Does Prothena Corporation plc's Balance Sheet Show?

| Cash and cash equivalents | $308 million |
| --- | --- |
| Long-term debt | Not reported |
| Total assets | $327 million |
| Total liabilities | $46 million |
| Shareholders' equity | $280 million |
| Current ratio | 7.7x |

Balance sheet values are as of the end of fiscal 2025. Income statement figures describe a whole year; balance sheet figures describe a single day, so the two answer different questions.

## Where These Numbers Come From

Every figure on this page is a value Prothena Corporation plc reported in its own SEC filings, read from the SEC's XBRL data (accession 0001559053-26-000008 for fiscal year 2025). Ratios are computed from those reported values. Figures were retrieved on October 7, 2026; a later amendment or a new annual report can change them, and the filing itself always takes precedence over this summary.

Each fiscal year is labeled by the calendar year in which it ended, so a company that names the same period differently in its own filings (many retailers whose year ends in January) may use another label. A year is left out of the table when the SEC data set holds no value for it. A figure shown as "Not reported" means the company did not file a value under the standard tag Swoopr reads, not that the amount was zero. This page is educational and describes reported history only; it is not a forecast or a recommendation.

## Frequently Asked Questions

### What was Prothena Corporation plc's revenue in fiscal 2025?

Prothena Corporation plc reported revenue of $10 million for the fiscal year ended December 31, 2025, according to its SEC filings.

### What is Prothena Corporation plc's operating margin?

Prothena Corporation plc's operating margin was -2216.4% in fiscal 2025: operating income of -$215 million on revenue of $10 million.

### How much free cash flow did Prothena Corporation plc generate?

Prothena Corporation plc did not report both operating cash flow and capital expenditures under the standard tags for fiscal 2025, so free cash flow is not computed here.

## References

- [SEC EDGAR: PROTHENA CORP PUBLIC LTD CO Form 10-K filed February 27, 2026](https://www.sec.gov/Archives/edgar/data/1559053/000155905326000008/prta-20251231.htm)
- [SEC EDGAR: PROTHENA CORP PUBLIC LTD CO annual and quarterly filings](https://www.sec.gov/cgi-bin/browse-edgar?action=getcompany&CIK=1559053&type=10-K)
- [SEC: EDGAR application programming interfaces (XBRL frames and submissions data)](https://www.sec.gov/search-filings/edgar-application-programming-interfaces)

## Related Pages

- [Prothena Corporation plc company dossier](https://www.getswoopr.com/stocks/companies/prothena-corporation-plc/)
- [Prothena Corporation plc financial metrics](https://www.getswoopr.com/stocks/companies/prothena-corporation-plc/financial-metrics/)
- [Prothena Corporation plc financial risk indicators](https://www.getswoopr.com/stocks/companies/prothena-corporation-plc/risks-monitoring/)
- [Prothena Corporation plc business model and revenue mix](https://www.getswoopr.com/stocks/companies/prothena-corporation-plc/business-model/)
- [Fundamental analysis guides](https://www.getswoopr.com/learn/fundamental-analysis/)

[Swoopr Editorial Team](https://www.getswoopr.com/authors/swoopr-editorial-team/)

Swoopr's editorial team produces independent investment education content. Content is for educational purposes only and does not constitute personalized investment advice. See our [editorial policy](https://www.getswoopr.com/legal/editorial-policy/) and [corrections policy](https://www.getswoopr.com/legal/corrections-policy/).