---
title: "OPKO Health Inc. Financial Metrics Guide"
description: "OPKO Health Inc. revenue, margins, cash flow and balance sheet figures by fiscal year, taken from its SEC filings, with the ratios computed and explained."
canonical: https://www.getswoopr.com/stocks/companies/opko-health-inc/financial-metrics/
source: "Swoopr Investment: https://www.getswoopr.com"
---

# OPKO Health Inc. Financial Metrics Guide

## Direct Answer

> OPKO Health Inc. reported revenue of $607 million for the fiscal year ended December 31, 2025, with an operating margin of -19.3% and net income of -$226 billion, according to its SEC filings. Revenue fell 14.9% from the prior year.

## What Are OPKO Health Inc.'s Key Financial Figures?

| Fiscal year | FY2025ended December 31, 2025 | FY2024ended December 31, 2024 | FY2023ended December 31, 2023 | FY2022ended December 31, 2022 |
| --- | --- | --- | --- | --- |
| Revenue | $607 million | $713 million | $863 million | $1.0 billion |
| Operating income | -$117 million | -$152 million | -$157 million | -$226 million |
| Operating margin | -19.3% | -21.3% | -18.2% | -22.5% |
| Net income | -$226 billion | -$53.2 billion | -$189 billion | -$328 billion |
| Net margin | -37187.0% | -7463.3% | -21871.9% | -32703.3% |
| Operating cash flow | -$179 million | -$183 million | -$28 million | -$95 million |
| Capital expenditures | $12 million | $25 million | $16 million | $25 million |
| Free cash flow | -$191 million | -$208 million | -$44 million | -$120 million |

Operating margin widened by 2.0 percentage points between fiscal 2024 and 2025, which separates pricing and cost discipline from revenue growth alone. Free cash flow (operating cash flow minus capital expenditures) was -$191 million against net income of -$226 billion; cash generation covered reported earnings.

![Bar chart of OPKO Health Inc. revenue, operating income, net income for fiscal 2022 to 2025. In fiscal 2025, revenue was $607 million, operating income negative $117 million and net income negative $226 billion.](https://www.getswoopr.com/images/charts/opko-health-inc-metrics-revenue-profit.webp)
*OPKO Health Inc. revenue, operating income and net income by fiscal year, from the figures in the table above. Select the chart to open it full size.*

![Line chart of OPKO Health Inc. operating margin and net margin for fiscal 2022 to 2025. In fiscal 2025, operating margin was -19.3% and net margin was -37187.0%.](https://www.getswoopr.com/images/charts/opko-health-inc-metrics-margins.webp)
*OPKO Health Inc. operating margin and net margin by fiscal year: operating income and net income as a share of revenue. Select the chart to open it full size.*

![Bar chart of OPKO Health Inc. operating cash flow, capital expenditures, free cash flow for fiscal 2022 to 2025. In fiscal 2025, operating cash flow was negative $179 million, capital expenditures was $12 million, free cash flow was negative $191 million.](https://www.getswoopr.com/images/charts/opko-health-inc-metrics-cash-flow.webp)
*OPKO Health Inc. operating cash flow, capital expenditures and free cash flow by fiscal year. Select the chart to open it full size.*

## What Does OPKO Health Inc.'s Balance Sheet Show?

| Cash and cash equivalents | $364 million |
| --- | --- |
| Long-term debt | $2 million |
| Total assets | $1.9 billion |
| Total liabilities | $664 million |
| Shareholders' equity | $1.3 billion |
| Current ratio | 4.0x |

Balance sheet values are as of the end of fiscal 2025. Income statement figures describe a whole year; balance sheet figures describe a single day, so the two answer different questions.

## Where These Numbers Come From

Every figure on this page is a value OPKO Health Inc. reported in its own SEC filings, read from the SEC's XBRL data (accession 0001193125-26-076596 for fiscal year 2025). Ratios are computed from those reported values. Figures were retrieved on October 12, 2026; a later amendment or a new annual report can change them, and the filing itself always takes precedence over this summary.

Each fiscal year is labeled by the calendar year in which it ended, so a company that names the same period differently in its own filings (many retailers whose year ends in January) may use another label. A year is left out of the table when the SEC data set holds no value for it. A figure shown as "Not reported" means the company did not file a value under the standard tag Swoopr reads, not that the amount was zero. This page is educational and describes reported history only; it is not a forecast or a recommendation.

## Frequently Asked Questions

### What was OPKO Health Inc.'s revenue in fiscal 2025?

OPKO Health Inc. reported revenue of $607 million for the fiscal year ended December 31, 2025, according to its SEC filings.

### What is OPKO Health Inc.'s operating margin?

OPKO Health Inc.'s operating margin was -19.3% in fiscal 2025: operating income of -$117 million on revenue of $607 million.

### How much free cash flow did OPKO Health Inc. generate?

Operating cash flow of -$179 million less capital expenditures of $12 million gives free cash flow of -$191 million for fiscal 2025.

## References

- [SEC EDGAR: OPKO HEALTH, INC. Form 10-K filed February 26, 2026](https://www.sec.gov/Archives/edgar/data/944809/000119312526076596/opk-20251231.htm)
- [SEC EDGAR: OPKO HEALTH, INC. annual and quarterly filings](https://www.sec.gov/cgi-bin/browse-edgar?action=getcompany&CIK=944809&type=10-K)
- [SEC: EDGAR application programming interfaces (XBRL frames and submissions data)](https://www.sec.gov/search-filings/edgar-application-programming-interfaces)

## Related Pages

- [OPKO Health Inc. company dossier](https://www.getswoopr.com/stocks/companies/opko-health-inc/)
- [OPKO Health Inc. financial metrics](https://www.getswoopr.com/stocks/companies/opko-health-inc/financial-metrics/)
- [OPKO Health Inc. financial risk indicators](https://www.getswoopr.com/stocks/companies/opko-health-inc/risks-monitoring/)
- [OPKO Health Inc. business model and revenue mix](https://www.getswoopr.com/stocks/companies/opko-health-inc/business-model/)
- [Fundamental analysis guides](https://www.getswoopr.com/learn/fundamental-analysis/)

[Swoopr Editorial Team](https://www.getswoopr.com/authors/swoopr-editorial-team/)

Swoopr's editorial team produces independent investment education content. Content is for educational purposes only and does not constitute personalized investment advice. See our [editorial policy](https://www.getswoopr.com/legal/editorial-policy/) and [corrections policy](https://www.getswoopr.com/legal/corrections-policy/).
