---
title: "Krystal Biotech Inc. Metrics Guide"
description: "Krystal Biotech Inc. revenue, margins, cash flow and balance sheet figures by fiscal year, taken from its SEC filings, with the ratios computed and explained."
canonical: https://www.getswoopr.com/stocks/companies/krystal-biotech-inc/financial-metrics/
source: "Swoopr Investment: https://www.getswoopr.com"
---

# Krystal Biotech Inc. Financial Metrics Guide

## Direct Answer

> Krystal Biotech Inc. reported revenue of $389 million for the fiscal year ended December 31, 2025, with an operating margin of 41.5% and net income of $205 million, according to its SEC filings. Revenue grew 33.9% from the prior year.

## What Are Krystal Biotech Inc.'s Key Financial Figures?

| Fiscal year | FY2025ended December 31, 2025 | FY2024ended December 31, 2024 | FY2023ended December 31, 2023 | FY2022ended December 31, 2022 |
| --- | --- | --- | --- | --- |
| Revenue | $389 million | $291 million | $51 million | $0 |
| Operating income | $161 million | $66 million | -$110 million | -$145 million |
| Operating margin | 41.5% | 22.6% | -216.2% | n/a |
| Net income | $205 million | $89 million | $11 million | -$140 million |
| Net margin | 52.6% | 30.7% | 21.6% | n/a |
| Operating cash flow | $201 million | $123 million | -$89 million | -$101 million |
| Capital expenditures | $12 million | $4 million | $12 million | $53 million |
| Free cash flow | $189 million | $119 million | -$101 million | -$154 million |

Operating margin widened by 18.8 percentage points between fiscal 2024 and 2025, which separates pricing and cost discipline from revenue growth alone. Free cash flow (operating cash flow minus capital expenditures) was $189 million against net income of $205 million; cash generation fell short of reported earnings, which is worth reconciling in the cash flow statement.

![Bar chart of Krystal Biotech Inc. revenue, operating income, net income for fiscal 2022 to 2025. In fiscal 2025, revenue was $389 million, operating income $161 million and net income $205 million.](https://www.getswoopr.com/images/charts/krystal-biotech-inc-metrics-revenue-profit.webp)
*Krystal Biotech Inc. revenue, operating income and net income by fiscal year, from the figures in the table above. Select the chart to open it full size.*

![Line chart of Krystal Biotech Inc. operating margin and net margin for fiscal 2022 to 2025. In fiscal 2025, operating margin was 41.5% and net margin was 52.6%.](https://www.getswoopr.com/images/charts/krystal-biotech-inc-metrics-margins.webp)
*Krystal Biotech Inc. operating margin and net margin by fiscal year: operating income and net income as a share of revenue. Select the chart to open it full size.*

![Bar chart of Krystal Biotech Inc. operating cash flow, capital expenditures, free cash flow for fiscal 2022 to 2025. In fiscal 2025, operating cash flow was $201 million, capital expenditures was $12 million, free cash flow was $189 million.](https://www.getswoopr.com/images/charts/krystal-biotech-inc-metrics-cash-flow.webp)
*Krystal Biotech Inc. operating cash flow, capital expenditures and free cash flow by fiscal year. Select the chart to open it full size.*

## What Does Krystal Biotech Inc.'s Balance Sheet Show?

| Cash and cash equivalents | $496 million |
| --- | --- |
| Long-term debt | Not reported |
| Total assets | $1.3 billion |
| Total liabilities | $114 million |
| Shareholders' equity | $1.2 billion |
| Current ratio | 10.0x |

Balance sheet values are as of the end of fiscal 2025. Income statement figures describe a whole year; balance sheet figures describe a single day, so the two answer different questions.

## Where These Numbers Come From

Every figure on this page is a value Krystal Biotech Inc. reported in its own SEC filings, read from the SEC's XBRL data (accession 0001711279-26-000016 for fiscal year 2025). Ratios are computed from those reported values. Figures were retrieved on October 7, 2026; a later amendment or a new annual report can change them, and the filing itself always takes precedence over this summary.

Each fiscal year is labeled by the calendar year in which it ended, so a company that names the same period differently in its own filings (many retailers whose year ends in January) may use another label. A year is left out of the table when the SEC data set holds no value for it. A figure shown as "Not reported" means the company did not file a value under the standard tag Swoopr reads, not that the amount was zero. This page is educational and describes reported history only; it is not a forecast or a recommendation.

## Frequently Asked Questions

### What was Krystal Biotech Inc.'s revenue in fiscal 2025?

Krystal Biotech Inc. reported revenue of $389 million for the fiscal year ended December 31, 2025, according to its SEC filings.

### What is Krystal Biotech Inc.'s operating margin?

Krystal Biotech Inc.'s operating margin was 41.5% in fiscal 2025: operating income of $161 million on revenue of $389 million.

### How much free cash flow did Krystal Biotech Inc. generate?

Operating cash flow of $201 million less capital expenditures of $12 million gives free cash flow of $189 million for fiscal 2025.

## References

- [SEC EDGAR: Krystal Biotech, Inc. Form 10-K filed February 17, 2026](https://www.sec.gov/Archives/edgar/data/1711279/000171127926000016/krys-20251231.htm)
- [SEC EDGAR: Krystal Biotech, Inc. annual and quarterly filings](https://www.sec.gov/cgi-bin/browse-edgar?action=getcompany&CIK=1711279&type=10-K)
- [SEC: EDGAR application programming interfaces (XBRL frames and submissions data)](https://www.sec.gov/search-filings/edgar-application-programming-interfaces)

## Related Pages

- [Krystal Biotech Inc. company dossier](https://www.getswoopr.com/stocks/companies/krystal-biotech-inc/)
- [Krystal Biotech Inc. financial metrics](https://www.getswoopr.com/stocks/companies/krystal-biotech-inc/financial-metrics/)
- [Krystal Biotech Inc. financial risk indicators](https://www.getswoopr.com/stocks/companies/krystal-biotech-inc/risks-monitoring/)
- [Krystal Biotech Inc. business model and revenue mix](https://www.getswoopr.com/stocks/companies/krystal-biotech-inc/business-model/)
- [Fundamental analysis guides](https://www.getswoopr.com/learn/fundamental-analysis/)

[Swoopr Editorial Team](https://www.getswoopr.com/authors/swoopr-editorial-team/)

Swoopr's editorial team produces independent investment education content. Content is for educational purposes only and does not constitute personalized investment advice. See our [editorial policy](https://www.getswoopr.com/legal/editorial-policy/) and [corrections policy](https://www.getswoopr.com/legal/corrections-policy/).
